Mer tyrosine kinase is ectopically expressed in acute lymphoblastic leukemia and associated with enhanced chemoresistance and disease progression.While such effects are generally ascribed to increased engagement of oncogenic pathways downstream of Mer stimulation by its ligand, Gas6, Mer has not been characterized beyond the scope of its signaling
Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury
Abstract Background There are limited options to diagnose acute kidney injury (AKI) in horses.Symmetric dimethylarginine (SDMA) is routinely used in human and small animal medicine.The aim of this study was to assess serum SDMA concentrations in healthy horses and horses with AKI.The objective of this study was to evaluate the association of: 1) ag